Jamie Dornan, Little Mix, Bastille and Britney sign up for Channel 4's Stand Up to Cancer night

Channel 4's Stand Up to Cancer campaign night is set to be bigger and better than ever before with a whole host of big names set to appear during the special night of programming.

Presented by Alan Carr, Davina McCall and Adam Hills, the evening will include live musical performances from Britney Spears, Little Mix, Bastille and Michael Buble.

Other highlights include the return of Streetmate - the iconic 90's dated show hosted by Davina McCall, a Last Leg Special, and Bear Grylls, Steve Jones and Jonathan Ross will be educating male viewers on the importance of checking their bits.

Jamie Dornan will appear on the night 

Jamie Dornan will appear on the night 

Celebrity Gogglebox returns featuring Noel Gallagher and Steve Coogan, and Jamie Dornan, Matthew McConaughey, David Tennant,  Olivia Colman and Eva Longoria  will all appear on the night.

This year's campaign runs from 7am until 2am on Friday 21 October 2016.